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BRAF Mutations In Colorectal Cancer Cause Resistance To Anti-EGFR Therapy, Study Finds

posted October 28, 2008 - 1:57pm
BRAF Mutations In Colorectal Cancer Cause Resistance To Anti-EGFR Therapy, Study Finds

Colorectal cancer is one of the most common cancers worldwide and a leading cause of cancer death. Once the disease has spread, the five-year survival rate is less than 10%. The targeted drugs cetuximab (Erbitux) and panitumumab (Vectibix) - monoclonal antibodies that inhibit EGFR - are used to treat patients with chemotherapy-resistant metastatic colorectal cancer. However, they are effective in only 10-


Website: http://www.vivnews.com/news/2008/10/braf-mutations...
Author: Clarissae
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